Breast cancer risk genetic marker
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A risk factor is anything that increases your chances of getting a disease, such as breast cancer. But having a risk factor, or even many, does not mean that you are sure to get the disease. Some risk factors for breast cancer are things you cannot change, such as getting older or inheriting certain gene changes. These make your risk of breast cancer higher. This is the main risk factor for breast cancer. Men can get breast cancer, too, but this disease is much more common in women than in men.
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BRCA Mutations: Cancer Risk and Genetic Testing
Genetic Testing for Cancer Risk | ohotech.info
People who inherit mutations in these genes are at an increased risk of developing breast cancer and ovarian cancer compared with the general population. The BRCA gene test is offered to those who are likely to have an inherited mutation based on personal or family history of breast cancer or ovarian cancer. The BRCA gene test isn't routinely performed on people at average risk of breast and ovarian cancers. The results of genetic testing aren't always clear. A positive result means you carry a gene mutation that increases your risk of cancer and you can work with your doctor to manage that risk. A negative result may mean that you don't have the mutation or that you might have a gene mutation doctors haven't discovered yet. Your test might also identify a gene variant that doctors aren't certain about.
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Molecular Markers for Breast Cancer: Prediction on Tumor Behavior
Until now, familial breast cancer has only partly been linkable to genetic risk markers. In a worldwide joint effort, researchers have now identified further genetic variants that affect the risk for breast cancer. Scientists expect that the results will lead to improved screening, earlier detection and better treatments for this disease. Ever since the wide media attention for Angelina Jolie's decision to have her breasts removed preventively, the genetic background of breast cancer has more or less been general knowledge.
It is possible to detect mutations in some cancer predisposing genes. Some mutations may not be detected using current technology. Genetic testing involves first searching for a gene mutation. After genetic counselling, a sample of blood is usually taken from a woman in the family who has developed breast cancer or ovarian cancer.